Fmoc-Homophe-OH is widely used in peptide synthesis as a building block. It is particularly valuable in solid-phase peptide synthesis (SPPS) due to the presence of the Fmoc (fluorenylmethyloxycarbonyl) protecting group, which can be easily removed under mild basic conditions. This compound is employed to introduce homophenylalanine residues into peptide chains, which can enhance the stability, bioavailability, or binding affinity of the synthesized peptides. It is commonly used in the development of therapeutic peptides, peptidomimetics, and research tools for studying protein-protein interactions or enzyme mechanisms. Additionally, it finds applications in the production of custom peptides for drug discovery and biochemical research.