Used in solid-phase peptide synthesis (SPPS) as a protecting group for amino acids, enabling selective deprotection during peptide chain assembly. It is particularly useful in synthesizing complex peptides and proteins, where orthogonal protection strategies are required. The Dde group can be selectively removed using hydrazine without affecting the Fmoc group, allowing for precise control over the synthesis process. This compound is essential in producing peptides for research, pharmaceuticals, and biotechnology applications, including drug development and biochemical studies. Its stability and compatibility with SPPS make it a valuable tool in peptide chemistry.