Used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), to introduce D-glutamic acid into peptide chains. It serves as a building block for creating peptides with specific sequences, often in pharmaceutical research and drug development. The Fmoc group protects the amino group during synthesis, ensuring selective reactions, while the methyl ester protects the carboxylic acid group. This compound is essential in producing peptides with modified structures, enhancing their stability, activity, or bioavailability. It is also utilized in the study of enzyme mechanisms and protein interactions due to its role in mimicking natural amino acids in synthetic peptides.