Proteinase K solution is widely used in molecular biology for its ability to digest proteins and remove contaminants from nucleic acid preparations. It is particularly effective in breaking down nucleases that could otherwise degrade DNA or RNA during extraction processes. This makes it a crucial component in the isolation of high-purity genetic material for applications such as PCR, cloning, and sequencing. Additionally, it is employed in tissue digestion for histology, in the preparation of samples for in situ hybridization, and in forensic science for extracting DNA from complex or degraded samples. Its robust activity across a range of temperatures and in the presence of denaturing agents like SDS enhances its utility in various laboratory and bioprocessing protocols.