Poly(vinyl sulfate) potassium salt is widely used in biochemical and biomedical research due to its ability to interact with proteins and other macromolecules. It is often employed as a polyanionic compound in studies involving protein binding, enzyme inhibition, and the stabilization of protein structures. In molecular biology, it serves as a tool for investigating the electrostatic interactions between negatively charged polymers and positively charged biomolecules. Additionally, it is utilized in the preparation of polyelectrolyte complexes, which are essential in drug delivery systems and tissue engineering. Its role in mimicking the behavior of natural polyanions, such as glycosaminoglycans, makes it valuable for studying cellular processes and extracellular matrix interactions. Furthermore, it is used as a standard substrate for measuring the activity of heparinase, an enzyme that degrades heparin, and in studies of biochemical processes involving sulfate groups in biological molecules.