Progoitrin is a glucosinolate compound used as a biochemical marker in plant breeding programs to assess goitrogenic potential in cruciferous crops such as rapeseed and mustard. It aids researchers in developing low-goitrin varieties to produce safer animal feed and edible oils. Additionally, it is studied for its role in interfering with iodine uptake in the thyroid gland, contributing to research on dietary causes of goiter. Found in certain oilseeds, progoitrin levels are monitored during food processing to minimize antinutritional effects in humans and livestock. Upon hydrolysis by myrosinase enzyme, progoitrin converts to goitrin, the active goitrogenic metabolite.