AG-1557 is primarily utilized in research settings as a selective inhibitor of protein kinase C (PKC). Its application is significant in studying cellular signaling pathways, particularly those involved in cell growth, differentiation, and apoptosis. Researchers employ AG-1557 to investigate the role of PKC in various diseases, including cancer, cardiovascular disorders, and neurological conditions. By inhibiting PKC, it helps in understanding the molecular mechanisms underlying these diseases and aids in the development of targeted therapies. Additionally, AG-1557 is used in pharmacological studies to explore potential therapeutic interventions and to assess the efficacy of PKC inhibitors in preclinical models.