1-BOC-4-chloropiperidine
≥97%
blur_circular Chemical Specifications
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) where the piperidine ring is a core structural motif. The BOC (tert-butoxycarbonyl) group acts as a protecting group for the nitrogen, allowing selective reactions at other sites of the molecule during multi-step syntheses. The presence of the chlorine atom provides a reactive handle for further transformations, such as cross-coupling reactions or nucleophilic substitutions, enabling the introduction of various functional groups. Commonly employed in the preparation of central nervous system (CNS) agents, including analgesics, antidepressants, and antipsychotics, due to the prevalence of piperidine derivatives in neuroactive compounds. Its stability and reactivity profile make it suitable for use in both research and industrial-scale drug development.
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