tert-Butyl 3-(pyrrolidine-1-carbonyl)piperidine-1-carboxylate
95%
Reagent
Code: #140733
CAS Number
937724-78-2
blur_circular Chemical Specifications
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Molecular Information
Weight
282.38 g/mol
Formula
C₁₅H₂₆N₂O₃
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Registry Numbers
MDL Number
MFCD09806109
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the development of bioactive molecules and drug candidates. Its structure, featuring a Boc-protected piperidine with a pyrrolidine amide substituent, supports the introduction of pyrrolidine and piperidine motifs, which are common in medicinal chemistry for enhancing metabolic stability and binding affinity. The tert-butoxycarbonyl (Boc) group protects the piperidine nitrogen, enabling regioselective reactions and facile deprotection. Commonly employed in the preparation of protease inhibitors and receptor modulators. Also utilized in research settings for library synthesis in structure-activity relationship (SAR) studies.
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