1-Boc-4-(3-Nitrobenzyl)piperazine
≥97%
blur_circular Chemical Specifications
description Product Description
Used primarily as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of active pharmaceutical ingredients (APIs) where piperazine derivatives are key structural components. Its protected piperazine core allows for selective reactions at other functional sites, making it valuable in multi-step organic syntheses. The presence of the nitrobenzyl group enables further transformations, such as reduction to an amine for use in coupling reactions. Commonly employed in medicinal chemistry for constructing drug candidates targeting neurological disorders, inflammation, and certain cancers. Also utilized in the preparation of receptor ligands, especially those interacting with serotonin, dopamine, or histamine systems. Suitable for solid-phase and solution-phase peptide-like synthesis due to the stability and ease of deprotection of the Boc group.
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