1-Boc-4-(4-Nitrophenyl)piperazine
98%
science Other reagents with same CAS 182618-86-6
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description Product Description
Used primarily as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of active pharmaceutical ingredients (APIs) where the Boc-protected piperazine scaffold is required. The presence of the nitrophenyl group allows for further functionalization through reduction to an aniline, enabling coupling reactions such as amide formation or diazotization. Its structure is valuable in medicinal chemistry for constructing drug candidates targeting central nervous system disorders, cardiovascular diseases, and certain cancers. The Boc (tert-butoxycarbonyl) group provides temporary protection of the piperazine nitrogen, allowing selective reaction at other sites, and can be easily removed under mild acidic conditions when needed. Commonly employed in multi-step organic syntheses in both research and industrial settings.
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