1-Boc-4-(4-Nitrophenyl)piperazine

98%

Reagent Code: #145793
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CAS Number 182618-86-6

science Other reagents with same CAS 182618-86-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 307.35 g/mol
Formula C₁₅H₂₁N₃O₄
thermostat Physical Properties
Boiling Point 456.6°C
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used primarily as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of active pharmaceutical ingredients (APIs) where the Boc-protected piperazine scaffold is required. The presence of the nitrophenyl group allows for further functionalization through reduction to an aniline, enabling coupling reactions such as amide formation or diazotization. Its structure is valuable in medicinal chemistry for constructing drug candidates targeting central nervous system disorders, cardiovascular diseases, and certain cancers. The Boc (tert-butoxycarbonyl) group provides temporary protection of the piperazine nitrogen, allowing selective reaction at other sites, and can be easily removed under mild acidic conditions when needed. Commonly employed in multi-step organic syntheses in both research and industrial settings.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿370.00
inventory 5g
10-20 days ฿1,600.00

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1-Boc-4-(4-Nitrophenyl)piperazine
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Used primarily as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of active pharmaceutical ingredients (APIs) where the Boc-protected piperazine scaffold is required. The presence of the nitrophenyl group allows for further functionalization through reduction to an aniline, enabling coupling reactions such as amide formation or diazotization. Its structure is valuable in medicinal chemistry for constructing drug candidates targeting central nervous system dis

Used primarily as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of active pharmaceutical ingredients (APIs) where the Boc-protected piperazine scaffold is required. The presence of the nitrophenyl group allows for further functionalization through reduction to an aniline, enabling coupling reactions such as amide formation or diazotization. Its structure is valuable in medicinal chemistry for constructing drug candidates targeting central nervous system disorders, cardiovascular diseases, and certain cancers. The Boc (tert-butoxycarbonyl) group provides temporary protection of the piperazine nitrogen, allowing selective reaction at other sites, and can be easily removed under mild acidic conditions when needed. Commonly employed in multi-step organic syntheses in both research and industrial settings.

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