Genipin is widely used in biomedical research and applications due to its ability to crosslink proteins and polymers. It is commonly employed as a natural crosslinking agent in the preparation of biocompatible hydrogels, which are used for tissue engineering, drug delivery systems, and wound healing. Its crosslinking properties enhance the mechanical strength and stability of biomaterials while maintaining low cytotoxicity. Additionally, genipin is utilized in the development of scaffolds for bone and cartilage regeneration, promoting cell adhesion and proliferation. It also serves as a blue pigment in food and cosmetic industries, offering a natural alternative to synthetic dyes. Furthermore, genipin has been studied for its potential antioxidant, anti-inflammatory, and anti-cancer effects, making it a candidate for therapeutic applications in treating various diseases.