Nystatin is widely used as an antifungal medication, particularly effective against Candida species. It is commonly applied to treat superficial fungal infections such as oral thrush, where it is administered as a mouthwash or lozenge. For skin infections, nystatin is available in cream or ointment form, directly applied to the affected area to alleviate symptoms and eradicate the infection. In cases of vaginal yeast infections, it is used in the form of suppositories or creams. Additionally, nystatin is employed in the treatment of intestinal candidiasis, often taken orally in liquid or tablet form, acting locally in the gastrointestinal tract due to its poor systemic absorption. Its ability to bind to ergosterol in fungal cell membranes makes it a potent antifungal agent, disrupting the integrity of the membrane and leading to cell death. This makes nystatin a crucial component in managing superficial and localized intestinal fungal infections, particularly in immunocompromised patients for prevention and treatment.