Daunomycinone is a key intermediate in the synthesis of anthracycline antibiotics, such as daunorubicin and doxorubicin. These antibiotics are essential in cancer chemotherapy, particularly for treating leukemias and solid tumors. As the aglycone core of these drugs, daunomycinone enables the formation of active pharmaceutical ingredients that intercalate DNA and inhibit topoisomerase II, preventing cancer cell replication. Its chemical structure facilitates modifications to enhance drug efficacy and minimize side effects in final formulations.