7-Ethyl-10-hydroxycamptothecin
98%
Reagent
Code: #110413
Alias
7-Ethyl-10-Hydroxycamptothecin
CAS Number
86639-52-3
science Other reagents with same CAS 86639-52-3
blur_circular Chemical Specifications
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Molecular Information
Weight
392.40 g/mol
Formula
C₂₂H₂₀N₂O₅
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Registry Numbers
MDL Number
MFCD06762720
thermostat
Physical Properties
Melting Point
217 °C
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Storage & Handling
Storage
-20°C
description Product Description
This compound is primarily used in the field of oncology as a potent anticancer agent. It functions by inhibiting the enzyme topoisomerase I, which is crucial for DNA replication in cancer cells. By blocking this enzyme, it prevents the cancer cells from dividing and proliferating, leading to their eventual death. It is often utilized in the treatment of various types of cancers, including colorectal, ovarian, and lung cancers. The compound is typically administered intravenously as part of chemotherapy regimens. Its efficacy and safety profile make it a valuable component in the management of advanced or metastatic cancers, often in combination with other chemotherapeutic agents to enhance therapeutic outcomes.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Purity (HPLC) | 98-100% |
| Specific Rotation [A]20/D (C=0.2, THF) | 17-26 |
| Water (Karl Fischer) | 0-10 |
| Appearance | Off-White To Yellow Powder |
| Solubility in DMSO | Faint yellow to yellow, clear, 1 mg/mL |
| NMR | Conforms To Structure |
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