Flubendazole
98%
Reagent
Code: #187480
Alias
[5-(4-Fluorobenzoyl)-1H-Benzimidazole-2-yl]carbamate; Fluorobendazole
CAS Number
31430-15-6
science Other reagents with same CAS 31430-15-6
blur_circular Chemical Specifications
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Molecular Information
Weight
313.28 g/mol
Formula
C₁₆H₁₂FN₃O₃
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Registry Numbers
EC Number
250-624-4
MDL Number
MFCD00871999
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Storage & Handling
Storage
2-8°C
description Product Description
Flubendazole is widely used as an anthelmintic agent, effective against a variety of parasitic worm infestations. It is commonly applied in veterinary medicine to treat gastrointestinal nematodes in livestock and companion animals. Its use extends to poultry, cattle, swine, and pets such as dogs and cats, where it controls roundworms, hookworms, and whipworms.
In human medicine, flubendazole is employed in the treatment of soil-transmitted helminthiases, including ascariasis, trichuriasis, and hookworm infection, particularly in resource-limited settings. It has also shown efficacy against tapeworms and is sometimes used off-label for neurocysticercosis, a parasitic infection of the central nervous system caused by larval tapeworms.
The compound works by inhibiting microtubule formation in parasites, disrupting their glucose uptake and leading to energy depletion and death. Due to poor systemic absorption when taken orally, it acts primarily within the gastrointestinal tract, making it suitable for intestinal parasites.
Flubendazole is being investigated for potential antitumor and antiviral properties, showing promise in preclinical studies for inhibiting cancer cell proliferation and certain RNA viruses, though these uses remain experimental.
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