Flumequine is primarily used as a veterinary antimicrobial agent, especially in aquaculture and livestock farming. It is effective against a range of bacterial infections, including those caused by Gram-negative and some Gram-positive bacteria. Commonly, it is applied in the treatment of enteric diseases in fish such as salmon, trout, and shrimp, where it helps control outbreaks of infections like vibriosis and enteric redmouth disease. Due to its broad-spectrum activity and ability to be absorbed effectively in aquatic environments, flumequine is often administered through medicated feed or water. It has also been used in poultry and swine to manage bacterial enteritis. However, its use is regulated in many countries because of concerns over antibiotic resistance and residue accumulation in food products. In some regions, its application in food-producing animals is banned or restricted to prevent potential public health risks.