(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)ethan-1-one(IbrutinibImpurity)

98%

Reagent Code: #231878
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CAS Number 1288338-95-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 428.49 g/mol
Formula C₂₄H₂₄N₆O₂
inventory_2 Storage & Handling
Storage Room temperature

description Product Description

This compound is a key impurity that occurs during the synthesis of ibrutinib, a Bruton's tyrosine kinase (BTK) inhibitor used to treat hematological malignancies such as chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL). Used primarily as a reference standard in pharmaceutical quality control and analytical testing during ibrutinib production, it helps ensure the purity and consistency of the final drug product. It is instrumental in validating analytical methods, such as HPLC and mass spectrometry (including LC-MS), to detect and quantify impurities in ibrutinib formulations. Due to its structural similarity to the active pharmaceutical ingredient, it aids in studying degradation pathways and establishing stability profiles of ibrutinib under various storage conditions. Controlled levels of this impurity support compliance with regulatory guidelines for drug safety and efficacy.

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Size Availability Unit Price Quantity
inventory 50mg
10-20 days ฿7,680.00

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