4'-Demethylepipodophyllotoxin

≥98%(HPLC)

Reagent Code: #174238
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CAS Number 6559-91-7

science Other reagents with same CAS 6559-91-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 400.384 g/mol
Formula C₂₁H₂₀O₈
thermostat Physical Properties
Melting Point 246-248°C
Boiling Point 626.5°C
inventory_2 Storage & Handling
Density 1.446 g/mL
Storage -20ºC

description Product Description

Used primarily as a key intermediate in the synthesis of chemotherapeutic agents like etoposide and teniposide. These drugs are widely employed in the treatment of various cancers, including testicular cancer, small cell lung cancer, lymphomas, and leukemias. The compound contributes to the inhibition of topoisomerase II, an enzyme critical for DNA replication and cell division, thereby inducing apoptosis in rapidly dividing cancer cells. Its role in enhancing the efficacy and specificity of anticancer drugs makes it valuable in oncology drug development.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿520.00
inventory 1g
10-20 days ฿1,440.00
inventory 5g
10-20 days ฿5,070.00
inventory 25g
10-20 days ฿18,630.00

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4'-Demethylepipodophyllotoxin
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Used primarily as a key intermediate in the synthesis of chemotherapeutic agents like etoposide and teniposide. These drugs are widely employed in the treatment of various cancers, including testicular cancer, small cell lung cancer, lymphomas, and leukemias. The compound contributes to the inhibition of topoisomerase II, an enzyme critical for DNA replication and cell division, thereby inducing apoptosis in rapidly dividing cancer cells. Its role in enhancing the efficacy and specificity of anticancer drug
Used primarily as a key intermediate in the synthesis of chemotherapeutic agents like etoposide and teniposide. These drugs are widely employed in the treatment of various cancers, including testicular cancer, small cell lung cancer, lymphomas, and leukemias. The compound contributes to the inhibition of topoisomerase II, an enzyme critical for DNA replication and cell division, thereby inducing apoptosis in rapidly dividing cancer cells. Its role in enhancing the efficacy and specificity of anticancer drugs makes it valuable in oncology drug development.
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