4'-Demethylepipodophyllotoxin
≥98%(HPLC)
Reagent
Code: #174238
CAS Number
6559-91-7
science Other reagents with same CAS 6559-91-7
blur_circular Chemical Specifications
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Molecular Information
Weight
400.384 g/mol
Formula
C₂₁H₂₀O₈
thermostat
Physical Properties
Melting Point
246-248°C
Boiling Point
626.5°C
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Storage & Handling
Density
1.446 g/mL
Storage
-20ºC
description Product Description
Used primarily as a key intermediate in the synthesis of chemotherapeutic agents like etoposide and teniposide. These drugs are widely employed in the treatment of various cancers, including testicular cancer, small cell lung cancer, lymphomas, and leukemias. The compound contributes to the inhibition of topoisomerase II, an enzyme critical for DNA replication and cell division, thereby inducing apoptosis in rapidly dividing cancer cells. Its role in enhancing the efficacy and specificity of anticancer drugs makes it valuable in oncology drug development.
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