(S)-()-Camptothecin

≥99%(HPLC)

Reagent Code: #127033
label
Alias Camptothecin; 4-Ethyl-4-hydroxy-1H-pyran[3',4':6,7]indolizine[1,2]quinoline-3,14(4H,12H)-dione
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CAS Number 7689-03-4

science Other reagents with same CAS 7689-03-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 348.35 g/mol
Formula C₂₀H₁₆N₂O₄
badge Registry Numbers
MDL Number MFCD00081076
thermostat Physical Properties
Melting Point 260 °C (dec.)(lit.)
inventory_2 Storage & Handling
Storage 2~8°C

description Product Description

Used primarily in cancer treatment, it inhibits the enzyme topoisomerase I, which is crucial for DNA replication in cancer cells. This action leads to the interruption of DNA synthesis and induces apoptosis in malignant cells. It serves as a key precursor for synthesizing more potent chemotherapeutic agents like irinotecan and topotecan, which are FDA-approved for treating colorectal and ovarian cancers, respectively. Additionally, ongoing research explores its potential in combating other diseases, including viral infections and autoimmune disorders, due to its mechanism of action on cellular DNA processes.

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Test Parameter Specification
Purity (%) 99-100%
Appearance Light yellow to brown powder, crystals, or solid

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿1,780.00
inventory 1g
10-20 days ฿3,990.00
inventory 5g
10-20 days ฿12,860.00

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(S)-()-Camptothecin
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Used primarily in cancer treatment, it inhibits the enzyme topoisomerase I, which is crucial for DNA replication in cancer cells. This action leads to the interruption of DNA synthesis and induces apoptosis in malignant cells. It serves as a key precursor for synthesizing more potent chemotherapeutic agents like irinotecan and topotecan, which are FDA-approved for treating colorectal and ovarian cancers, respectively. Additionally, ongoing research explores its potential in combating other diseases, including viral infections and autoimmune disorders, due to its mechanism of action on cellular DNA processes.
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