(S)-()-Camptothecin
≥99%(HPLC)
Reagent
Code: #127033
Alias
Camptothecin; 4-Ethyl-4-hydroxy-1H-pyran[3',4':6,7]indolizine[1,2]quinoline-3,14(4H,12H)-dione
CAS Number
7689-03-4
science Other reagents with same CAS 7689-03-4
blur_circular Chemical Specifications
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Molecular Information
Weight
348.35 g/mol
Formula
C₂₀H₁₆N₂O₄
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Registry Numbers
MDL Number
MFCD00081076
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Physical Properties
Melting Point
260 °C (dec.)(lit.)
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Storage & Handling
Storage
2~8°C
description Product Description
Used primarily in cancer treatment, it inhibits the enzyme topoisomerase I, which is crucial for DNA replication in cancer cells. This action leads to the interruption of DNA synthesis and induces apoptosis in malignant cells. It serves as a key precursor for synthesizing more potent chemotherapeutic agents like irinotecan and topotecan, which are FDA-approved for treating colorectal and ovarian cancers, respectively. Additionally, ongoing research explores its potential in combating other diseases, including viral infections and autoimmune disorders, due to its mechanism of action on cellular DNA processes.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Purity (%) | 99-100% |
| Appearance | Light yellow to brown powder, crystals, or solid |
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