Palladium(II) iodide is primarily used in organic synthesis as a catalyst for various chemical reactions. It plays a significant role in cross-coupling reactions, such as the Suzuki-Miyaura and Heck reactions, which are essential for forming carbon-carbon bonds in the production of pharmaceuticals, agrochemicals, and advanced materials. Additionally, it is employed in the synthesis of complex organic molecules, including natural products and fine chemicals. Palladium(II) iodide is also utilized in the preparation of palladium complexes, which serve as precursors for further catalytic applications. Its ability to facilitate selective transformations makes it valuable in research and industrial processes.