(5-Bromo-2-methoxyphenoxy)(tert-butyl)dimethylsilane

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Reagent Code: #140830
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CAS Number 177329-71-4

science Other reagents with same CAS 177329-71-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 317.2941 g/mol
Formula C₁₃H₂₁BrO₂Si
badge Registry Numbers
MDL Number MFCD11855959
thermostat Physical Properties
Boiling Point 307.8±32.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.166±0.06 g/cm3(Predicted)
Storage 2-8°C, Inert Gas

description Product Description

Used as a protecting group reagent in organic synthesis, particularly in the construction of complex molecules such as natural products and pharmaceuticals. The tert-butyldimethylsilyl (TBS) group provides stability to sensitive functional groups, especially alcohols, under a variety of reaction conditions. The bromo and methoxy substituents on the phenoxy ring allow for further functionalization via cross-coupling reactions, making this silyl ether a valuable intermediate in multi-step syntheses. Its application is prominent in medicinal chemistry where selective protection and deprotection are required to achieve desired molecular architectures.

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inventory 1g
10-20 days ฿3,160.00

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(5-Bromo-2-methoxyphenoxy)(tert-butyl)dimethylsilane
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Used as a protecting group reagent in organic synthesis, particularly in the construction of complex molecules such as natural products and pharmaceuticals. The tert-butyldimethylsilyl (TBS) group provides stability to sensitive functional groups, especially alcohols, under a variety of reaction conditions. The bromo and methoxy substituents on the phenoxy ring allow for further functionalization via cross-coupling reactions, making this silyl ether a valuable intermediate in multi-step syntheses. Its ap

Used as a protecting group reagent in organic synthesis, particularly in the construction of complex molecules such as natural products and pharmaceuticals. The tert-butyldimethylsilyl (TBS) group provides stability to sensitive functional groups, especially alcohols, under a variety of reaction conditions. The bromo and methoxy substituents on the phenoxy ring allow for further functionalization via cross-coupling reactions, making this silyl ether a valuable intermediate in multi-step syntheses. Its application is prominent in medicinal chemistry where selective protection and deprotection are required to achieve desired molecular architectures.

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