tert-butyl(4-(benzyloxy)-1-iodonaphthalen-2-yl)carbamate
95%
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description Product Description
Used as an intermediate in organic synthesis, particularly in the preparation of naphthalene-based compounds for pharmaceutical and agrochemical research, including the development of anti-cancer agents and bioactive molecules. The iodine at position 1 enables selective functionalization through cross-coupling reactions, such as palladium-catalyzed transformations with organometallic compounds. The tert-butyl carbamate protects the amine functionality at position 2 during reaction sequences, allowing for controlled deprotection later. The benzyloxy group at position 4 acts as a protecting group for the phenolic hydroxy, which can be removed under reductive conditions like hydrogenation with metal catalysts. This structure makes it highly valuable for constructing complex, specific intermediates in the synthesis of molecules with targeted biological activity.
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