Topotecan hydrochloride
Analytical standards, ≥99% (HPLC)
Reagent
Code: #239646
Alias
Topological Tekang Hydrochloric acid
CAS Number
119413-54-6
science Other reagents with same CAS 119413-54-6
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Molecular Information
Weight
457.91 g/mol
Formula
C₂₃H₂₄ClN₃O₅
thermostat
Physical Properties
Melting Point
213-218°C
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Storage & Handling
Storage
-20°C
description Product Description
Used in chemotherapy to treat certain types of cancer, particularly ovarian cancer, small cell lung cancer, and cervical cancer. It works by inhibiting topoisomerase I, an enzyme involved in DNA replication, leading to DNA damage and cancer cell death. Due to its ability to cross the blood-brain barrier, it is also considered in cases where cancer has spread to the central nervous system. Administered intravenously, it is often used when other treatments have failed, making it a valuable option in advanced or recurrent disease settings.
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