(7S,9S)-9-Acetyl-6,7,9,11-tetrahydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione

97%

Reagent Code: #235613
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CAS Number 60660-75-5

science Other reagents with same CAS 60660-75-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 368.34 g/mol
Formula C₂₀H₁₆O₇
badge Registry Numbers
MDL Number MFCD09952466
thermostat Physical Properties
Boiling Point 625.6°C at 760 mmHg
inventory_2 Storage & Handling
Storage Room temperature, dry seal

description Product Description

This compound is a key intermediate in the synthesis of anthracycline antitumor antibiotics used in cancer treatment, particularly for leukemia and lymphoma. The resulting antibiotics function by intercalating into DNA and inhibiting topoisomerase II, which prevents cancer cell replication and induces apoptosis. Due to their high potency, they are commonly incorporated into combination chemotherapy regimens. Their clinical use is constrained by potential cardiotoxicity, necessitating careful monitoring. This intermediate is also employed in research to investigate DNA damage, apoptosis, and related biochemical mechanisms in cell cultures.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿25,060.00
inventory 250mg
10-20 days ฿49,890.00

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(7S,9S)-9-Acetyl-6,7,9,11-tetrahydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione
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This compound is a key intermediate in the synthesis of anthracycline antitumor antibiotics used in cancer treatment, particularly for leukemia and lymphoma. The resulting antibiotics function by intercalating into DNA and inhibiting topoisomerase II, which prevents cancer cell replication and induces apoptosis. Due to their high potency, they are commonly incorporated into combination chemotherapy regimens. Their clinical use is constrained by potential cardiotoxicity, necessitating careful monitoring.

This compound is a key intermediate in the synthesis of anthracycline antitumor antibiotics used in cancer treatment, particularly for leukemia and lymphoma. The resulting antibiotics function by intercalating into DNA and inhibiting topoisomerase II, which prevents cancer cell replication and induces apoptosis. Due to their high potency, they are commonly incorporated into combination chemotherapy regimens. Their clinical use is constrained by potential cardiotoxicity, necessitating careful monitoring. This intermediate is also employed in research to investigate DNA damage, apoptosis, and related biochemical mechanisms in cell cultures.

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