Olaparib
10mM in DMSO
Reagent
Code: #221236
CAS Number
763113-22-0
blur_circular Chemical Specifications
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Molecular Information
Weight
434.46 g/mol
Formula
C₂₄H₂₃FN₄O₃
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Registry Numbers
MDL Number
MFCD13185161
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in the treatment of ovarian, breast, fallopian tube, and prostate cancers with specific genetic mutations, particularly BRCA1 and BRCA2. It works by inhibiting the PARP enzyme, which cancer cells rely on to repair their DNA. In tumors with BRCA mutations, this inhibition leads to accumulated DNA damage and ultimately cancer cell death. This targeted approach improves outcomes in patients with these genetic profiles and is often used when other treatments have failed. It is taken orally and allows for long-term management of certain advanced cancers.
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