Used primarily as a key intermediate in the synthesis of potent anticancer drugs like etoposide, teniposide, and etopophos. These derivatives are widely employed in chemotherapy to treat various cancers, including lung cancer, testicular cancer, lymphomas, and leukemias. The compound’s ability to inhibit topoisomerase II makes it valuable in disrupting DNA replication in cancer cells, leading to cell death. Due to its strong cytotoxic properties, it is also studied for developing new antitumor agents and targeted cancer therapies. Additionally, it serves as a lead compound in structural modifications to enhance efficacy and reduce side effects in next-generation oncology drugs.