N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
95%
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This compound is primarily used in the field of nucleic acid chemistry and molecular biology. It serves as a key intermediate in the synthesis of modified nucleosides, which are essential for the development of oligonucleotides. These oligonucleotides are widely employed in research applications such as gene synthesis, PCR, and sequencing. The compound’s protective groups, like the bis(4-methoxyphenyl)(phenyl)methyl (DMT) group, ensure selective deprotection during solid-phase synthesis, enabling precise construction of DNA or RNA strands. Its application is critical in the production of therapeutic oligonucleotides, including antisense drugs and siRNA, which are used to target and modulate gene expression in various diseases. Additionally, it finds utility in the study of nucleotide analogs for antiviral or anticancer drug development.
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