Lobeline
≥98%
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Used in research for its interaction with nicotinic acetylcholine receptors, particularly as a tool to study dopamine release and neuronal pathways related to addiction. Investigated for potential use in treating nicotine dependence due to its ability to mimic some effects of nicotine while reducing withdrawal symptoms, though clinical trials have not led to approved therapies. Also explored for its respiratory stimulant properties, having been historically used to counteract respiratory depression. Shows activity in crossing the blood-brain barrier, making it relevant in studies on central nervous system disorders, including potential applications in Alzheimer's and Parkinson's disease research. Not currently approved for widespread clinical use but remains of interest in neuropharmacology and substance abuse research.
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