Used primarily as a research tool in neuroscience and pharmacology, it acts as a selective antagonist of the TRPV1 receptor, which is involved in the perception of pain and heat. This makes it valuable in studies exploring pain signaling pathways and the development of new analgesic drugs. It is also employed to investigate the role of TRPV1 in inflammatory conditions, cough reflexes, and thermoregulation. Due to its ability to block capsaicin-induced responses, it helps differentiate TRPV1-mediated effects from other mechanisms in cellular and animal models. Its application remains largely confined to laboratory settings rather than clinical use.