Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of central nervous system (CNS) agents. Its structural configuration supports the creation of bioactive molecules with improved selectivity and metabolic stability. Commonly employed in the preparation of serotonin and norepinephrine reuptake inhibitors, where the trans configuration and methoxy group enhance binding affinity to target receptors. Also utilized in the design of novel analgesics and antidepressants due to its favorable stereochemistry and polarity. Additionally, serves as a building block in medicinal chemistry for optimizing drug candidates during lead optimization.