Lappaconitine
10mM in DMSO
Reagent
Code: #201886
CAS Number
32854-75-4
blur_circular Chemical Specifications
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Molecular Information
Weight
584.7 g/mol
Formula
C₃₂H₄₄N₂O₈
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Storage & Handling
Storage
-20°C
description Product Description
Used as a non-opioid analgesic in clinical medicine, particularly in Russia and some Asian countries, for the treatment of moderate to severe pain including postoperative and neuralgic pain. Its analgesic effect is attributed to interaction with voltage-gated sodium channels, leading to stabilization of neuronal membranes and reduced pain signal transmission. Due to its potential toxicity, it is administered under strict medical supervision, often in combination with other agents to enhance efficacy and reduce side effects. Also investigated for antiarrhythmic properties, though clinical use remains limited to pain management.
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