Used in research and development for inflammatory and autoimmune diseases, particularly as a tool to study the role of interferon-gamma (IFN-γ) in immune responses. It serves as a reference standard in immunoassays and neutralization studies to evaluate the activity of other anti-IFN-γ antibodies. Commonly applied in preclinical studies for conditions like Crohn’s disease, ulcerative colitis, and other Th1-mediated disorders where IFN-γ signaling plays a key role. Also utilized in quality control during the manufacturing of biologics targeting the IFN-γ pathway.