Anti-IFNa1 Reference Antibody (sifalimumab)
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Used in research and development for autoimmune diseases, particularly systemic lupus erythematosus (SLE). It functions by neutralizing interferon-alpha (IFN-α), a key cytokine involved in the inflammatory response associated with lupus. By blocking IFN-α activity, it helps reduce disease activity and symptoms in clinical trials. It serves as a reference standard in immunoassays and therapeutic antibody development targeting the type I interferon pathway. Also utilized in pharmacokinetic and pharmacodynamic studies to evaluate the efficacy of anti-interferon therapies.
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