Epothilone B is primarily utilized in cancer research and treatment due to its ability to stabilize microtubules, which is crucial for inhibiting cell division in rapidly proliferating cancer cells. It is particularly studied for its potential in treating cancers that have developed resistance to other microtubule-targeting drugs like taxanes. In clinical settings, it is explored as a chemotherapeutic agent for various malignancies, including breast, prostate, and ovarian cancers. Additionally, its mechanism of action makes it a valuable tool in biochemical studies to understand microtubule dynamics and cell cycle regulation. Research is ongoing to optimize its efficacy and reduce side effects, making it a promising candidate in oncology.