Fatostatin A
10mM in DMSO
Reagent
Code: #186967
CAS Number
298197-04-3
blur_circular Chemical Specifications
scatter_plot
Molecular Information
Weight
375.33 g/mol
Formula
C₁₈H₁₈N₂S·HBr
inventory_2
Storage & Handling
Storage
-20°C
description Product Description
Fatostatin A is primarily used in research settings to study lipid metabolism and its regulation. It acts as a potent inhibitor of SREBP (sterol regulatory element-binding proteins), which are key transcription factors involved in the synthesis of fatty acids and cholesterol. By blocking SREBP activation, Fatostatin A effectively reduces lipogenesis, making it a valuable tool in investigating metabolic disorders such as obesity, fatty liver disease, and type 2 diabetes.
It has also shown potential in cancer research due to the dependence of certain tumor cells on lipid synthesis for rapid growth. Inhibiting SREBP with Fatostatin A can suppress proliferation and induce apoptosis in some cancer cell lines. Additionally, it is explored for its antiviral properties, as some viruses rely on host lipid metabolism for replication, particularly in infections like hepatitis C and dengue.
Due to its ability to modulate cellular lipid homeostasis, Fatostatin A serves as a lead compound for developing therapies targeting metabolic syndrome and related conditions.
shopping_cart Available Sizes & Pricing
Cart
No products
Subtotal:
0.00
Total
0.00
THB