GPR81 agonist 1 is primarily utilized in research settings to study the role of the GPR81 receptor, which is involved in metabolic regulation and signaling pathways. It is particularly used to investigate its effects on adipose tissue, where activation of GPR81 can influence lipid metabolism and reduce lipolysis. This makes it a potential candidate for exploring therapeutic strategies for metabolic disorders, such as obesity and type 2 diabetes. Additionally, it is employed in studies focusing on anti-inflammatory responses, as GPR81 activation has been linked to modulation of inflammatory processes. Its application extends to understanding its role in cancer biology, where GPR81 signaling may impact tumor growth and progression.