Used in immunology research to modulate T-cell activation, particularly in studying autoimmune diseases and transplant rejection. Selectively inhibits the PKC-theta pathway, which plays a key role in T-cell receptor signaling. Investigated for potential therapeutic use in conditions like rheumatoid arthritis, multiple sclerosis, and type 1 diabetes due to its ability to suppress inflammatory immune responses without broad immunosuppression. Also employed in cancer immunotherapy research to enhance the efficacy of other immune-modulating agents by fine-tuning T-cell activity.