N-(3-Chloro-4-Fluorophenyl)-7-Methoxy-6-Aminoquinazolin-4-Amine

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Reagent Code: #217541
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CAS Number 179552-75-1

science Other reagents with same CAS 179552-75-1

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Weight 318.73 g/mol
Formula C₁₅H₁₂ClFN₄O
inventory_2 Storage & Handling
Storage Room temperature, dry

description Product Description

Used as a key intermediate in the synthesis of epidermal growth factor receptor (EGFR) inhibitors, particularly in targeted cancer therapies. Its structure enables selective binding to tyrosine kinase domains, making it valuable in developing anticancer drugs, especially for non-small cell lung cancer. The compound's fluorinated and chlorinated aromatic system enhances binding affinity and metabolic stability, improving drug efficacy. It is primarily employed in pharmaceutical research and development for generating novel kinase inhibitors with improved potency and selectivity.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿860.00
inventory 1g
10-20 days ฿3,970.00
inventory 25g
10-20 days ฿42,000.00
inventory 5g
10-20 days ฿13,900.00

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N-(3-Chloro-4-Fluorophenyl)-7-Methoxy-6-Aminoquinazolin-4-Amine
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Used as a key intermediate in the synthesis of epidermal growth factor receptor (EGFR) inhibitors, particularly in targeted cancer therapies. Its structure enables selective binding to tyrosine kinase domains, making it valuable in developing anticancer drugs, especially for non-small cell lung cancer. The compound's fluorinated and chlorinated aromatic system enhances binding affinity and metabolic stability, improving drug efficacy. It is primarily employed in pharmaceutical research and development for generating novel kinase inhibitors with improved potency and selectivity.
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