N-(3-Chloro-4-Fluorophenyl)-7-Methoxy-6-Aminoquinazolin-4-Amine
98%
Reagent
Code: #217541
CAS Number
179552-75-1
science Other reagents with same CAS 179552-75-1
blur_circular Chemical Specifications
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Molecular Information
Weight
318.73 g/mol
Formula
C₁₅H₁₂ClFN₄O
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of epidermal growth factor receptor (EGFR) inhibitors, particularly in targeted cancer therapies. Its structure enables selective binding to tyrosine kinase domains, making it valuable in developing anticancer drugs, especially for non-small cell lung cancer. The compound's fluorinated and chlorinated aromatic system enhances binding affinity and metabolic stability, improving drug efficacy. It is primarily employed in pharmaceutical research and development for generating novel kinase inhibitors with improved potency and selectivity.
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