N-(5-(3,5-Dicyano-1,2,6-trimethyl-1,4-dihydropyridin-4-yl)-6-fluoro-7-methyl-1H-indazol-3-yl)-2-ethylbenzamide
98%
Reagent
Code: #214755
CAS Number
2377576-35-5
science Other reagents with same CAS 2377576-35-5
blur_circular Chemical Specifications
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Molecular Information
Weight
468.53 g/mol
Formula
C₂₇H₂₅FN₆O
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Registry Numbers
MDL Number
MFCD34662962
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Physical Properties
Boiling Point
617.9±55.0 °C(Predicted)
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Storage & Handling
Density
1.32±0.1 g/cm3(Predicted)
Storage
2-8°C, sealed, dry, light-proof
description Product Description
Used in pharmaceutical research as a potent inhibitor of cyclin-dependent kinases (CDKs), particularly CDK2 and CDK9, making it a candidate for anticancer drug development. It shows promise in disrupting cell cycle progression and transcription in tumor cells, especially in hematological malignancies. Its structure enables high selectivity and improved metabolic stability, supporting its evaluation in preclinical studies for targeted cancer therapies.
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