Motesanib Diphosphate (AMG-706)

10mM in DMSO

Reagent Code: #204329
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CAS Number 857876-30-3

science Other reagents with same CAS 857876-30-3

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Weight 569.44 g/mol
Formula C₂₂H₂₃N₅O·₂H₃PO₄
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in targeted cancer therapy, particularly in the treatment of advanced solid tumors and thyroid cancer. Acts as a selective inhibitor of multiple receptor tyrosine kinases, including vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3), platelet-derived growth factor receptor (PDGFR), and stem cell factor receptor (KIT). By blocking these receptors, it interferes with tumor angiogenesis and cell proliferation, thereby suppressing tumor growth and metastasis. Investigated in clinical trials for non-small cell lung cancer and other malignancies due to its ability to disrupt signaling pathways critical for tumor survival. Its oral bioavailability makes it a convenient option for long-term treatment regimens in oncology.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿9,200.00

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Motesanib Diphosphate (AMG-706)
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Used in targeted cancer therapy, particularly in the treatment of advanced solid tumors and thyroid cancer. Acts as a selective inhibitor of multiple receptor tyrosine kinases, including vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3), platelet-derived growth factor receptor (PDGFR), and stem cell factor receptor (KIT). By blocking these receptors, it interferes with tumor angiogenesis and cell proliferation, thereby suppressing tumor growth and metastasis. Investigated in clinical trials for non-small cell lung cancer and other malignancies due to its ability to disrupt signaling pathways critical for tumor survival. Its oral bioavailability makes it a convenient option for long-term treatment regimens in oncology.
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