Ethyl 7-bromo-4-chloroquinazoline-2-carboxylate
97%
science Other reagents with same CAS 1189105-79-0
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description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors for cancer treatment. Its structure allows for selective modification, making it valuable in creating compounds that target specific signaling pathways in tumor cells. Commonly employed in medicinal chemistry research to build quinazoline-based drug candidates with improved potency and selectivity. Also utilized in the preparation of EGFR (epidermal growth factor receptor) inhibitors, which play a role in managing non-small cell lung cancer and other malignancies. Its bromo and chloro functional groups enable further cross-coupling reactions, facilitating the introduction of diverse substituents during drug optimization.
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