2-Bromo-7-(Tert-Butoxycarbonyl)-5,6,7,8-Tetrahydroimidazo[1,2-A]Pyrazine-3-Carboxylic Acid
98%
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Used as a key intermediate in the synthesis of pharmaceutical compounds, featuring a tetrahydroimidazo[1,2-a]pyrazine core that incorporates imidazole and piperazine structures. It plays a crucial role in developing drugs targeting neurological disorders, cancer, and inflammatory diseases, including kinase inhibitors and other bioactive molecules. The bromine group at position 2 acts as a good leaving group for nucleophilic substitution reactions, facilitating covalent bonding with protein targets. The tert-butoxycarbonyl (Boc) protecting group on the nitrogen prevents unwanted reactivity during intermediate steps, enabling precise synthetic control. The carboxylic acid at position 3 allows for further modifications, such as amide or anhydride formation, essential for constructing complex heterocyclic systems in medicinal chemistry.
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