Used in pharmaceutical research as a potent and selective inhibitor of cyclin-dependent kinases (CDKs), particularly CDK8 and CDK19. It modulates transcriptional regulation by targeting the mediator complex, making it a valuable tool compound in oncology studies, especially in cancers driven by dysregulated transcription such as acute myeloid leukemia and colorectal cancer. Demonstrates high cellular permeability and metabolic stability, supporting its use in in vitro and in vivo models to investigate CDK-dependent signaling pathways. Also serves as a lead structure for developing novel anticancer agents due to its favorable selectivity profile and potency.