6-Amino-2-(butylamino)-9-((6-(2-(dimethylamino)ethoxy)pyridin-3-yl)methyl)-7,9-dihydro-8H-purin-8-one
98%
science Other reagents with same CAS 1059070-10-8
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description Product Description
Used in research as a potent and selective inhibitor of cyclin-dependent kinases (CDKs), particularly CDK9, which plays a key role in transcription regulation. This compound is valuable in studying cancer cell proliferation and survival, especially in hematological malignancies. It shows promise in disrupting oncogenic transcription by targeting the CDK9/cyclin T complex, leading to downregulation of short-lived oncoproteins like Mcl-1. Due to its ability to penetrate cells and modulate transcriptional pathways, it is widely applied in preclinical studies for anticancer drug development. Its structural features allow for high selectivity, reducing off-target effects in cellular assays.
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