4-Bromo-2-Chloro-1-Isothiocyanatobenzene

98%

Reagent Code: #154036
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CAS Number 98041-69-1

science Other reagents with same CAS 98041-69-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 248.53 g/mol
Formula C₇H₃BrClNS
badge Registry Numbers
MDL Number MFCD00041051
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of bioactive molecules that require selective functionalization of aromatic rings. Its isothiocyanate group readily reacts with amines and thiols, making it valuable in the preparation of thiourea derivatives and heterocyclic compounds. It is also employed in medicinal chemistry for constructing kinase inhibitors and antimicrobial agents. Due to the presence of multiple halogen atoms, it serves as a versatile building block in cross-coupling reactions such as Suzuki and Heck reactions, enabling the formation of complex aromatic structures. Additionally, it finds use in the development of covalent inhibitors where the isothiocyanate acts as an electrophilic warhead targeting nucleophilic residues in proteins.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿590.00
inventory 1g
10-20 days ฿1,250.00
inventory 5g
10-20 days ฿5,960.00
inventory 25g
10-20 days ฿27,220.00

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4-Bromo-2-Chloro-1-Isothiocyanatobenzene
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Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of bioactive molecules that require selective functionalization of aromatic rings. Its isothiocyanate group readily reacts with amines and thiols, making it valuable in the preparation of thiourea derivatives and heterocyclic compounds. It is also employed in medicinal chemistry for constructing kinase inhibitors and antimicrobial agents. Due to the presence of multiple halogen atoms, it serv

Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of bioactive molecules that require selective functionalization of aromatic rings. Its isothiocyanate group readily reacts with amines and thiols, making it valuable in the preparation of thiourea derivatives and heterocyclic compounds. It is also employed in medicinal chemistry for constructing kinase inhibitors and antimicrobial agents. Due to the presence of multiple halogen atoms, it serves as a versatile building block in cross-coupling reactions such as Suzuki and Heck reactions, enabling the formation of complex aromatic structures. Additionally, it finds use in the development of covalent inhibitors where the isothiocyanate acts as an electrophilic warhead targeting nucleophilic residues in proteins.

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