Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other biologically active molecules. Its iodine functionality allows for further modification via cross-coupling reactions such as Suzuki or Heck couplings, enabling the introduction of aromatic or heteroaromatic systems. The tert-butyl protecting group stabilizes the carboxylate during multi-step syntheses and can be easily removed under acidic conditions when needed. Commonly employed in medicinal chemistry for constructing isoindoline-based scaffolds, which are found in various drug candidates targeting cancer, inflammation, and central nervous system disorders.