tert-Butyl 4-bromoisoindoline-2-carboxylate

95%

Reagent Code: #145540
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CAS Number 1035235-27-8

science Other reagents with same CAS 1035235-27-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 298.18 g/mol
Formula C₁₃H₁₆BrNO₂
thermostat Physical Properties
Boiling Point 363.2°C
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other bioactive molecules. Its protected amine and bromo-functionalized isoindoline core allow for selective cross-coupling reactions and further derivatization, making it valuable in medicinal chemistry for constructing complex heterocyclic systems. Commonly employed in solid-phase and solution-phase peptide-like synthesis due to the stability and ease of deprotection of the tert-butyl carbamate (Boc) group. Also utilized in the preparation of proteolysis-targeting chimeras (PROTACs) and other targeted therapeutics.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 50mg
10-20 days ฿320.00
inventory 1g
10-20 days ฿3,320.00
inventory 5g
10-20 days ฿11,640.00
inventory 25g
10-20 days ฿51,170.00
inventory 250mg
10-20 days ฿970.00

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tert-Butyl 4-bromoisoindoline-2-carboxylate
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Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other bioactive molecules. Its protected amine and bromo-functionalized isoindoline core allow for selective cross-coupling reactions and further derivatization, making it valuable in medicinal chemistry for constructing complex heterocyclic systems. Commonly employed in solid-phase and solution-phase peptide-like synthesis due to the stability and ease of deprotection of the

Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other bioactive molecules. Its protected amine and bromo-functionalized isoindoline core allow for selective cross-coupling reactions and further derivatization, making it valuable in medicinal chemistry for constructing complex heterocyclic systems. Commonly employed in solid-phase and solution-phase peptide-like synthesis due to the stability and ease of deprotection of the tert-butyl carbamate (Boc) group. Also utilized in the preparation of proteolysis-targeting chimeras (PROTACs) and other targeted therapeutics.

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