1-Boc-3-bromo-5-nitro-1H-indazole

95%

Reagent Code: #173680
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CAS Number 473416-22-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 342.15 g/mol
Formula C₁₂H₁₂BrN₃O₄
badge Registry Numbers
MDL Number MFCD11617131
inventory_2 Storage & Handling
Storage Room temperature, dry

description Product Description

Used as a key intermediate in the synthesis of biologically active indazole derivatives, particularly in pharmaceutical research. The Boc-protected indazole scaffold allows for selective functionalization at the bromo and nitro positions, enabling sequential cross-coupling reactions such as Suzuki or Buchwald–Hartwig aminations. Commonly employed in the development of kinase inhibitors and other medicinal agents targeting cancer and inflammatory diseases. The nitro group can be reduced to an amine for further derivatization, expanding its utility in library synthesis for drug discovery. Stable under standard handling conditions, it is suitable for use in multi-step synthetic routes requiring selective deprotection and coupling strategies.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿8,160.00
inventory 5g
10-20 days ฿18,510.00

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