3-((tert-Butyldiphenylsilyl)oxy)-2,2-dimethylpropanoic acid
98%
Reagent
Code: #141472
CAS Number
480450-04-2
blur_circular Chemical Specifications
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Molecular Information
Weight
356.53 g/mol
Formula
C₂₁H₂₈O₃Si
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Registry Numbers
MDL Number
MFCD28966754
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of complex organic molecules, particularly in pharmaceuticals and natural products. Its primary role is as a protected hydroxy acid building block, where the silyl ether group acts as a protecting group for alcohols during multi-step syntheses. The bulky tert-butyldiphenylsilyl group provides steric shielding, enhancing stability and selectivity in reactions. Commonly employed in peptide chemistry and macrolide synthesis, it allows for selective functional group transformations and improves solubility in organic solvents. Also utilized in the preparation of prodrugs and biologically active compounds where controlled deprotection is required.
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